Cyprodinil
Product Specifications
UNSPSC Description
Cyprodinil is an anilinopyrimidine broad-spectrum fungicide that inhibits the biosynthesis of methionine in phytopathogenic fungi. Cyprodinil inhibits mycelial cell growth of B. cinerea, P. herpotrichoides, and H. oryzae on amino acid-free media (IC50s=0.44, 4.8, and 0.03 µM, respectively). Cyprodinil acts as an androgen receptor (AR) agonist (EC50=1.91 µM) in the absence of the AR agonist DHT and inhibits the androgenic effect of DHT (IC50=15.1 µM).
Target Antigen
Androgen Receptor; Fungal
Type
Reference compound
Related Pathways
Anti-infection;Vitamin D Related/Nuclear Receptor
Field of Research
Infection; Endocrinology
Assay Protocol
https://www.medchemexpress.com/cyprodinil.html
Purity
99.36
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CC1=CC(C2CC2)=NC(NC3=CC=CC=C3)=N1
Molecular Weight
225.29
References & Citations
[1]Masner, P., et al. Possible methionine biosynthesis inhibition by pyrimidinamine fungicides. Pestic. Sci. 42(3),163-166 (1994).|[2]Frances Orton, et al. Widely used pesticides with previously unknown endocrine activity revealed as in vitro antiandrogens. Environ Health Perspect. 2011 Jun;119(6):794-800.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-116214/Cyprodinil-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-116214/Cyprodinil-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
121552-61-2
Available Sizes
Curated Selection
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