CB07-Exatecan
CB07-Exatecan is an ADC drug-Linker conjugate that can be used for the synthesis of ADCs. ADC conjugated with CB07-Exatecan and trastuzumab inhibits the growth of HER2-positive cancer cells. CB07-Exatecan can be used in cancer research[1].
Product Specifications
CAS Number
[2879247-31-9]
UNSPSC
12352203
Target
Drug-Linker Conjugates for ADC; Topoisomerase
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related; Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/cb07-exatecan.html
Purity
98.97
Solubility
DMSO : 100 mg/mL (ultrasonic; warming)
Smiles
Molecular Formula
C71H94FN11O22
Molecular Weight
1472.56
References & Citations
[1]Weijia Tang, et al. Method for treating her2-positive solid tumor. Patent WO2023198079A1.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
ADC Related
Clinical Information
No Development Reported
Isoform
Camptothecins
Available Sizes
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