Cephalexin (monohydrate)

Cephalexin (Cefalexin) monohydrate is a potent, orally active new semisynthetic cephalosporin antibiotic with a broad antibacterial spectrum. Cephalexin (Cefalexin) monohydrate has antibacterial activity against a wide variety of gram-positive and gram-negative bacteria. Cephalexin (Cefalexin) monohydrate targets penicillin-binding proteins (PBPs) to inhibit bacterial cell wall assembly. Cephalexin (Cefalexin) monohydrate is used for the research of pneumonia, strep throat, and bacterial endocarditis, et al[1][2].

Product Specifications

CAS Number

[23325-78-2]

Product Name Alternative

Cefalexin hydrate; Cephacillin hydrate

UNSPSC

12352005

Hazard Statement

H302, H312, H332

Target

Antibiotic; Bacterial; Penicillin-binding protein (PBP)

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection; Cancer

Assay Protocol

https://www.medchemexpress.com/cephalexin-monohydrate.html

Purity

99.61

Solubility

DMSO : 6.67 mg/mL (ultrasonic) |H2O : 2 mg/mL (ultrasonic)

Smiles

O=C(C(N12)=C(C)CS[C@]2([H])[C@H](NC([C@H](N)C3=CC=CC=C3)=O)C1=O)O.O

Molecular Formula

C16H19N3O5S

Molecular Weight

365.40

Precautions

H302, H312, H332

References & Citations

[1]Cho H, et, al. Beta-lactam antibiotics induce a lethal malfunctioning of the bacterial cell wall synthesis machinery. Cell. 2014 Dec 4;159 (6) :1300-11. |[2]Buck RE, et, al. Cefadroxil, a new broad-spectrum cephalosporin. Antimicrob Agents Chemother. 1977 Feb;11 (2) :324-30.