Clavulanate (lithium)
Clavulanate lithium is a potent β-lactamase inhibitor and acts as an antibiotic[1][2].
Product Specifications
CAS Number
[61177-44-4]
UNSPSC
12352005
Hazard Statement
H360
Target
Antibiotic; Bacterial; Beta-lactamase
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/clavulanate-lithium.html
Concentration
10mM
Purity
99.87
Solubility
DMSO : 4.17 mg/mL (ultrasonic; warming; heat to 60°C) |H2O : 33.33 mg/mL (ultrasonic)
Smiles
O=C([C@@H](/C(O[C@]1([H])C2)=C/CO)N1C2=O)O[Li]
Molecular Formula
C8H8LiNO5
Molecular Weight
205.09
Precautions
H360
References & Citations
[1]Reading C, et al. Clavulanic Acid: a Beta-Lactamase-Inhibiting Beta-Lactam from Streptomyces clavuligerus. Antimicrob Agents Chemother. 1977 May; 11 (5) : 852–857.|[2]Stokes DH, et al. Bactericidal effects of amoxycillin/clavulanic acid against intracellular Legionella pneumophila in tissue culture studies. J Antimicrob Chemother. 1989 Apr;23 (4) :547-56.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
β-lactam
Citation 01
BioRxiv. 2024 May 10.|Nat Commun. 2022 Mar 2;13 (1) :1116.|Biomed Res Int. 2018 Jul 2:2018:3579832.|Eur J Pharmacol. 2024 Dec 5:984:177017.|Genomics. 2022 Nov;114 (6) :110527.|Int J Mol Sci. 2023 Oct 27;24 (21) :15657.|J Antimicrob Chemother. 2025 Nov 5:dkaf408.
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