PIN - GenPrice UK

Pin1 is a peptidylprolyl isomerase (PPI) that targets phosphorylated Ser or Thr residues followed by a Pro (S/TP) . Isomerization of phosphorylated Ser or Thr residues may alter protein confirmation and, subsequently, modify activity. Pin1 is overexpressed in many human breast cancers, and has been shown to modify numerous proteins including p53, NFκB, cJun, cyclin D1, and βcatenin.

Product Specifications

Synonyms

PIN1; DOD; UBL5

NCBI Gene ID

5300

UniProt

Q13526

Accession Number

NP_006212.1

Accession Number mRNA

NM_006221.3

Chromosomal Location

19p13

Reactivity

Anti-Human

Cross Reactivity

Human

Target Antigen

Recombinant human PIN

Clone

(#9S2)

Applications

Purification Method

Protein G chromatography

Assay Protocol

Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.

Form

Lyophilized

Buffer

PBS

Reconstitution

PBS

Storage Conditions

Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.