GITR

GITR (glucocorticoid-induced tumor necrosis factor receptor), also named AITR (activation-inducible TNFreceptor superfamily member) and TNFRSF18, is a 228amino acid typeI transmembrane protein belonging to the TNFreceptor superfamily. The GITR cytoplasmic domain has striking similarity to the cytoplasmic domain of 4-1BB and CD27.

Product Specifications

Synonyms

Tnfrsf18; AITR; Gitr

NCBI Gene ID

21936

UniProt

O35714

Accession Number

NP_033426.1

Accession Number mRNA

NM_009400.2

Chromosomal Location

4; 4 E

Reactivity

Anti-Mouse

Cross Reactivity

Mouse

Target Antigen

Mouse T cells

Clone

(#7C13)

Applications

IHC (P), FC

Purification Method

Protein G/A chromatography

Assay Protocol

Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.

Form

Lyophilized

Buffer

PBS

Reconstitution

PBS

Storage Conditions

Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.