Follistatin
Follistatin belongs to a group of structurally-diverse diffusible proteins that binds to TGF-beta ligands and inhibit their activity by hindering access to signaling receptors. This naturally occurring antagonist binds to Activin, BMP-2, -4, -6, -7, Myostatin, GDF-11, and TGF-beta1. Follistatin is expressed in the pituitary, ovaries, decidual cells of the endometrium, and in some other tissues. Recombinant human Follistatin is a 31.5 kDa protein containing 288 amino acids including 36 cysteine residues.
Product Specifications
Synonyms
FST; FS
NCBI Gene ID
10468
UniProt
P19883
Accession Number
NP_006341.1
Accession Number mRNA
NM_006350
Chromosomal Location
5q11.2
Reactivity
Human
Cross Reactivity
Chicken, Mouse, Human, Rat
Sequence
Endotoxin
< 0.1 ng/µg of protein (< 1EU/µg)
Purity
> 95% by SDS-PAGE & HPLC analyses
Bioactivity
Length
288
Form
Lyophilized
Molecular Weight
31.5 kDa
Host or Source
E. coli
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