FGFR-3 (IIIb) S249C/Fc Chimera, soluble
Product Specifications
Synonyms
Fibroblast growth factor receptor 3, FGFR-3/ CD333
NCBI Gene ID
2261
UniProt
P22607-2
Accession Number
NP_001156685.1
Accession Number mRNA
NM_001163213.1
Chromosomal Location
4q16.3
Reactivity
Human
Cross Reactivity
Human
Label
Fc-Tag
Sequence
ESLGTEQRVVGRAAEVPGPEPGQQEQLVFGSGDAVELSCPPPGGGPMGPTVWVKDGTGLVPSERVLVGPQRLQVLNASHEDSGAYSCRQRLTQRVLCHFSVRVTDAPSSGDDEDGEDEAEDTGVDTGAPYWTRPERMDKKLLAVPAANTVRFRCPAAGNPTPSISWLKNGREFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQTYTLDVLERCPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDGTPYVTVLKSWISESVEADVRLRLANVSERDGGEYLCRATNFIGVAEKAFWLSVHGPRAAEEELVEADEAGSVYAGTRSDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSREEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPMLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGK
Bioactivity
Measured by its binding ability to aFGF and FGF2 in a functional ELISA. In addition recombinant human soluble FGFR-3 (IIIb) S249C/Fc Chimera also binds to immobilized recombinant human FGF9 and FGF18.
Length
585
Form
Lyophilized
Molecular Weight
65.0kDa
Host or Source
Insect cells
N Terminal Sequence
ESLGT
Curated Selection
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