FGF-2 (basic) 146 aa
FGF-basic is one of 23 known members of the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-basic is a non-glycosylated heparin binding growth factor that is expressed in the brain, pituitary, kidney, retina, bone, testis, adrenal gland liver, monocytes, epithelial cells and endothelial cells. FGF-basic signals through FGFR 1b, 1c, 2c, 3c and 4. Recombinant Human FGF-basic (146 a.a.) is a 16.4 kDa protein consisting of 146 amino acid residues.
Product Specifications
Synonyms
FGF2; BFGF; FGFB; HBGF-2; basic Fibroblast growth factor (bFGF) ; Heparin binding growth factor-3, Prostatropin
NCBI Gene ID
2247
UniProt
P09038
Accession Number
NP_001997.5
Accession Number mRNA
NM_002006.4
Chromosomal Location
4q26
Reactivity
Human
Cross Reactivity
Human
Sequence
Assay Protocol
Endotoxin
< 0.1 ng/µg of protein (< 1EU/µg)
Purity
> 98% by SDS-PAGE & HPLC analyses
Bioactivity
Length
146
Form
Lyophilized
Buffer
5mM Tris, pH 7.6 + 150mM NaCl
Reconstitution
5mM Tris, pH 7.6
Molecular Weight
16.4 kDa
Storage Conditions
Host or Source
E. coli
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