Cystatin C

Cystatin C is a member of family 2 of the cystatin superfamily. It inhibits many cysteine proteases such as papain and Cathepsins B, H, K, L and S. It is ubiquitous in human tissues and body fluids. A point mutation in the gene coding for the 120 amino acid mature Cystatin C causes a hereditary form of amyloid angiopathy in which the protein variant (Leu 68 to Gln) is deposited in the cerebral arteries, leading to fatal cerebral hemorrhage.

Product Specifications

Synonyms

Cst3; CysC

NCBI Gene ID

13010

UniProt

P21460

Accession Number

NP_034106.2

Accession Number mRNA

NM_009976.3

Chromosomal Location

2 G3; 2 84.0 Cm

Reactivity

Anti-Mouse

Cross Reactivity

Mouse

Target Antigen

Mouse recombinant Cystatin C

Clone

(#4E59)

Applications

Purification Method

Protein G/A chromatography

Assay Protocol

Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.

Form

Lyophilized

Buffer

PBS

Reconstitution

PBS

Storage Conditions

Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.