CD244 (SLAMF4)
2B4, also known as CD244, is a cell surface glycoprotein belonging to the CD2 subgroup of the immunoglobulin superfamily. It acts as a high-affinity receptor for CD48. It is expressed by natural killer (NK) cells and CD8+ T cell subsets. It can regulate killing by CD8+ T cells and NK cells, and IFN-gamma secretion by NK cells. It may also regulate NK cell and T cell proliferation.
Product Specifications
Synonyms
CD244; 2B4; NAIL; Nmrk; NKR2B4; SLAMF4
NCBI Gene ID
51744
UniProt
Q9BZW8
Accession Number
NP_057466
Accession Number mRNA
NM_016382
Chromosomal Location
1q23.3
Reactivity
Anti-Human
Cross Reactivity
Human
Target Antigen
Human recombinant CD244 (EC domain)
Clone
(#7D24)
Applications
WB
Purification Method
Protein G chromatography
Assay Protocol
Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Form
Lyophilized
Buffer
PBS
Reconstitution
PBS
Storage Conditions
Host or Source
Mouse
Isotype
IgG2
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