CD105/Endoglin

The MJ7/18 monoclonal antibody reacts with the mouse CD105 molecule, also known as Endoglin. This 90 kDa disulfide-linked homodimer is expressed by vascular endothelial cells. It is suggested that CD105 functions in adhesion and embryonic angiogenesis.

Product Specifications

Synonyms

Eng endoglin; CD105; AI528660; AI662476; S-endoglin

NCBI Gene ID

13805

UniProt

Q63961

Accession Number

NP_031958

Accession Number mRNA

NM_007932

Chromosomal Location

2 B; 2 21.4 cM

Reactivity

Anti-Mouse

Cross Reactivity

Mouse

Target Antigen

Inflamed mouse skin

Clone

(#MJ7/18)

Applications

WB, IHC (F), IP, FC

Purification Method

Protein G chromatography

Assay Protocol

Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml.

Bioactivity

Western Blot: use at 1-5 µg/ml.

Form

Lyophilized

Buffer

PBS

Reconstitution

Water

Storage Conditions

The lyophilized antibody is stable for at least 2 years at -20°C. After sterile reconstitution the antibody is stable at 2-8°C for up to 6 months. Frozen aliquots are stable for at least 6 months when stored at -20°C. Addition of a carrier protein or 50% glycerol is recommended for frozen aliquots.