Cathepsin V

Cathepsin V (also known as Cathepsin L2 and U) is a cysteine protease of the papain family. It is expressed as a proenzyme in lysosomes, which can be autocatalytically converted to the mature form at pH 4.0. Cathepsin V shows high amino acid identity with Cathepsin L (77% for the proenzymes and 80% for the mature enzymes) . However, Cathepsin V is specifically expressed in the thymus, testis, and corneal epithelium whereas Cathepsin L is expressed throughout the body.

Product Specifications

Synonyms

CTSL2; CTSU; CTSV; CATL2

NCBI Gene ID

1515

UniProt

O60911

Accession Number

NP_001324

Accession Number mRNA

NM_001333.3

Chromosomal Location

9q22.2

Reactivity

Anti-Human

Cross Reactivity

Human

Target Antigen

Recombinant human Cathepsin-V

Clone

(#9G24)

Applications

WB, IHC (P)

Purification Method

Protein G chromatography

Assay Protocol

Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.

Form

Lyophilized

Buffer

PBS

Reconstitution

PBS

Storage Conditions

Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.