Nonabine

Nonabine (BRL-4664), a cannabinoid, is a antiemetic agent. Nonabine activates CB1 receptor in the brainstem and enteric nervous system[1][2].

Product Specifications

CAS Number

[16985-03-8]

Product Name Alternative

BRL-4664

UNSPSC

12352005

Target

Cannabinoid Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/nonabine.html

Purity

99.95

Smiles

OC1=C2C(C3=CC=NC=C3)=CC(C)(OC2=CC(C(C(CCCCC)C)C)=C1)C

Molecular Formula

C25H33NO2

Molecular Weight

379.54

References & Citations

[1]Archer CB, et al. Antiemetic effect of nonabine in cancer chemotherapy: a double blind study comparing nonabine and chlorpromazine. Br Med J (Clin Res Ed) . 1983 Jan 29;286 (6362) :350-1. |[2]Shah S, et al. ASRA Pain Medicine consensus guidelines on the management of the perioperative patient on cannabis and cannabinoids. Reg Anesth Pain Med. 2023 Mar;48 (3) :97-117.