VPS35 Kit
Colorimetric measurement of VPS35
Product Specifications
Background
Vacuolar Protein Sorter-35 (VPS35) is a component of the retromer complex, which is essential for endosome-to-Golgi retrieval of membrane proteins. VPS35 mutations such as D620N have been linked to Parkinson’s Disease (PD) (1,2) and affect retromer function, protein homeostasis, and mitochondria (3).
Product Name Alternative
Vacuolar protein sorting-associated protein 35, MEM3, PARK17, VPS35 retromer complex component, maternal-embryonic 3, vesicle protein sortin 35, TCCCTA00141, FLJ10752
UNSPSC
12352203
Species Reactivity
Human,Mouse,Rat
Target
VPS35
Applications
ELISA kit used to quantitate VPS35 in samples.
Detection Method
Colorimetric Assay
Assay Type
Sandwich
Sample Type
Tissue | Cell Lysate
Detection Range
78.125 - 5000 pg/mL
Sensitivity
50 pg/mL
Weight
500
Components
Anti-VPS35 Immunoassay Plate | 5X VPS35 Extraction Reagent | Recombinant VPS35 Standard | Standard and Sample Diluent (Red) | 10X Wash Buffer Concentrate | Anti-VPS35 Biotinylated Antibody Concentrate | Anti-VPS35 Biotinylated Antibody Diluent (Green) | 100X Streptavidin:HRP Concentrate | Streptavidin: HRP Diluent (Purple) | TMB Substrate | Stop Solution
Precautions
Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
References & Citations
1. Vilarino-Guell, C. et al. (2011) Am J Hum Genet 89:162–167
2. Zimprich, A. et al. (2011) Am J Hum Genet 89:168–175
3. Rahman, A.A., Morrison, B.E. (2019) Neurosci 401:1-10.
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