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Tau Antibody (pThr217): Biotin

Mouse Anti-Human Tau (pThr217) Monoclonal IgG1 Kappa

Product Specifications

Background

This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type.

Specifications

Detects phosphorylation on Thr217

Product Name Alternative

Microtubule associated protein tau | phospho tau

Synonyms

Tau Antibody (pThr217), Clone 15B7: Biotin

UNSPSC

12352203

Gene ID

4137

Swiss Prot

P10636

Accession Number

NP_058519.3

Cellular Locus

Intracellular | Secreted

Host

Mouse

Species Reactivity

Human,Mouse,Rat

Immunogen

Synthetic peptide of Wild-type Human Tau (pThr217) AA 210-224: SRTPSLP-pT-PPTREPK

Target

Tau (pThr217)

Clonality

Monoclonal

Isotype

IgG1 κ

Clone

15B7

Conjugation

Biotin

Tissue Specificity

Brain | Skeletal Muscle

Validated Applications

WB,IHC,ICC/IF |ELISA

Purification

Protein G Purified

Limit Of Detection

A 1:1000 dilution of SMC-615 was sufficient for detection of Tau in 10 µg of Human, Mouse, Rat Tau Peptide (pThr217) by DB analysis using Goat Anti-Mouse IgG:HRP as the secondary antibody.

Concentration

1 mg/ml

Dilution

WB (1:1000); optimal dilutions for assays should be determined by the user.

Weight

0.1

Buffer

136.36mM Ethanolamine, and 9.55mM Sodium Bicarbonate in 95.45% PBS

Precautions

Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

Product MSDS

https://cdn.gentaur.com/products/400/11821711/msds/smc-615d-bi.pdf

CAS Number

9007-83-4

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