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NOS1/ nNOS Antibody: RPE

Mouse Anti-Human NOS1 Monoclonal IgG2a

Product Specifications

Background

nNOS/NOS I, also known as NC-NOS, or NOS type I, or Neuronal NOS, or produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. Nitric oxide production is mediated by members of the nitric oxide synthase (NOS) family. NOS catalyzes the oxidization of L-arginine to produce L-citrulline and NO. There are two constitutive isoforms, brain or neuronal NOS (b or nNOS, type I) & endothelial cell NOS (eNOS, type III), and one inducible isoform (iNOS, type II).

Specifications

Detects ~160.97 kDa.

Product Name Alternative

BNOS Antibody, Constitutive NOS Antibody, IHPS 1 Antibody, IHPS1 Antibody, N-NOS Antibody, NC-NOS Antibody, neuronal Nitric Oxide Synthase Antibody, Neuronal NOS Antibody, Nitric oxide synthase neuronal included Antibody, Nitric oxide synthase 1 (neuronal) Antibody, Nitric oxide synthase 1 Antibody, NNOS Antibody, NO Antibody, NOS 1 Antibody, NOS Antibody, NOS type I Antibody, NOS-I Antibody, NOS1 Antibody, NOS1_HUMAN Antibody

Synonyms

NOS1/ nNOS Antibody: RPE

UNSPSC

12352203

Gene ID

4842

Swiss Prot

P29475

Accession Number

NP_000611.1

Cellular Locus

Cell Membrane

Host

Mouse

Species Reactivity

Human,Mouse,Rat

Immunogen

Partial Human Recombinant NOS1 Protein

Target

NOS1

Clonality

Monoclonal

Isotype

IgG2a

Clone

J23

Conjugation

RPE

Tissue Specificity

Ubiquitously expressed; detected in skeletal muscle and brain, also in testis, lung and kidney.

Validated Applications

WB,IHC,ICC/IF

Purification

Protein A Purified

Limit Of Detection

A 1:1000 dilution of SMC-609 was sufficient for detection of NOS1/Nnos in 7.5 ug of Mouse Brain Cerebellum by ECL immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody.

Concentration

1 mg/ml

Dilution

WB (1:1000); optimal dilutions for assays should be determined by the user.

Weight

0.1

Buffer

95.64mM Phosphate, 2.48mM MES and 2mM EDTA

Precautions

Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

Product Datasheet

https://cdn.gentaur.com/products/400/11821643/datasheet/smc-609d-rpe.pdf

Product MSDS

https://cdn.gentaur.com/products/400/11821643/msds/smc-609d-rpe.pdf

CAS Number

9007-83-4

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