Sulfanilamide

Ulfanilamide (Sulphanilamide) is a potent and orally active sulfonamide antibiotic and can be a major intermediate of sulfamethoxazole biodegradation. Sulfanilamide also is a carbonic anhydrase inhibitor. Sulfanilamide shows inhibition on virus of lymphogranuloma venereum[1][2][3][4].

Product Specifications

CAS Number

[63-74-1]

Product Name Alternative

Sulphanilamide

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Antibiotic; Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/Sulfanilamide.html

Concentration

10mM

Purity

99.93

Solubility

DMSO : 100 mg/mL (ultrasonic) |H2O : 10 mg/mL (ultrasonic)

Smiles

O=S(C1=CC=C(N)C=C1)(N)=O

Molecular Formula

C6H8N2O2S

Molecular Weight

172.21

Precautions

H302, H315, H319, H335

References & Citations

[1]Liao X, et al. Antibiotic sulfanilamide biodegradation by acclimated microbial populations. Appl Microbiol Biotechnol. 2016 Mar;100 (5) :2439-47.|[2]Padeĭskaia EN, et al. Sravnitel'naia aktivnost' depo-sul'fanilamidov pri éksperimental'noĭ infektsii mysheĭ, vyzvannoĭ K1. pneumoniae [Comparative activity of depot sulfanilamides in experimental infection in mice caused by K1. pneumoniae]. Antibiotiki. 1980 Mar;25 (3) :193-8. |[3]T. MANN, et al. Sulphanilamide as a Specific Inhibitor of Carbonic Anhydrase. Nature, 1940, 146, 164-165.|[4]Findlay GM. The Action of Sulphanilamide on the Virus of Lymphogranuloma Venereum. Br J Exp Pathol. 1940 Dec;21 (6) :356–60.