Recombinant MAP2K6 (MEK6) Protein

<strong>Recombinant MAP2K6 (MEK6) Protein</strong>_x000D_ <strong>Catalog number:</strong> B2017586_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 10 µg_x000D_ <strong>Molecular Weight or Concentration:</strong> 38.78 kDa_x000D_ <strong>Supplied as:</strong> SOLUTION_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -80°C_x000D_ <strong>Keywords:</strong> Mitogen activated protein kinase kinase 6, SAPKK3, SAPKK-3, MEK6, MKK6, MAPKK6, PRKMK6, MAPK/ERK Kinase 6, SAPK Kinase, MEK_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Stein B, Brady H, Yang MX, Young DB, Barbosa MS. Cloning and characterization of MEK6, a novel member of the mitogen-activated protein kinase kinase cascade J Biol Chem. 1996 May 10;271(19):11427-33._x000D_ 2: Chen Z, Cobb MH. Regulation of stress-responsive mitogen-activated protein (MAP) kinase pathways by TAO2 J Biol Chem. 2001 May 11;276(19):16070-5._x000D_ 3: Hutchison M, Berman KS, Cobb MH. Isolation of TAO1, a protein kinase that activates MEKs in stress-activated protein kinase cascades J Biol Chem. 1998 Oct 30;273(44):28625-32._x000D_ 4: Efimova T, Broome AM, Eckert RL. Protein kinase Cdelta regulates keratinocyte death and survival by regulating activity and subcellular localization of a p38delta-extracellular signal-regulated kinase 1/2 complex Mol Cell Biol. 2004 Sep;24(18):8167-83._x000D_ 5: Berman K, McKay J, Avery L, Cobb M. Isolation and characterization of pmk-(1-3): three p38 homologs in Caenorhabditis elegans Mol Cell Biol Res Commun. 2001 Nov;4(6):337-44._x000D_ 6: Yuan J, Kang JL, Liao H, Wang XX, Nie ML, Shuai R, Deng C. Mitogen-activated Protein Kinase Kinase 6-fusion Protein (MAP2K6-FP) Potentiates the Anti-tumor effects of Paclitaxel in Ovarian Cancer Anticancer Agents Med Chem. 2015;15(10):1308-16._x000D_ 7: Guo Y, Yuan J, Yin S, Wang X, Shuai R, Kang J. MAP2K6-FP Enhances the Sensitiveness of Paclitaxel for Ovarian Cancer via Inducing Autophagy Int J Gynecol Cancer. 2017 Jul;27(6):1082-1087._x000D_ 8: Ben-Levy R, Hooper S, Wilson R, Paterson HF, Marshall CJ. Nuclear export of the stress-activated protein kinase p38 mediated by its substrate MAPKAP kinase-2 Curr Biol. 1998 Sep 24;8(19):1049-57._x000D_ 9: Khattar SK, Gulati P, Kundu PK, Singh V, Bughani U, Bajpai M, Saini KS. Enhanced soluble production of biologically active recombinant human p38 mitogen-activated-protein kinase (MAPK) in Escherichia coli Protein Pept Lett. 2007;14(8):756-60._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/24825433">10: Wang L, Huang J, Jiang M, Chen Q, Jiang Z, Feng H. CAMK1 phosphoinositide signal-mediated protein sorting and transport network in human hepatocellular carcinoma (HCC) by biocomputation Cell Biochem Biophys. 2014 Nov;70(2):1011-6. </a>_x000D_ _x000D_ <strong>Products Related to Recombinant MAP2K6 (MEK6) Protein can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>