Bleomycin B4

Bleomycin B4 (Phleomycin F) is an antibiotic. Bleomycin B4 has antitumor activity. Bleomycin B4 can be used for the research of cancer[1][2][3].

Product Specifications

CAS Number

[9060-11-1]

Product Name Alternative

Phleomycin F

UNSPSC

12352005

Target

Antibiotic

Type

Natural Products

Related Pathways

Anti-infection

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/bleomycin-b4.html

Purity

98.71

Solubility

DMSO : 25 mg/mL (ultrasonic)

Smiles

O[C@H]1[C@@H](OC(N)=O)[C@H](O)[C@@H](CO)O[C@@H]1O[C@@H]2[C@H](O[C@H]([C@H](NC(C3=C(C)C(N)=NC([C@@H](NC[C@H](C(N)=O)N)CC(N)=O)=N3)=O)C(N[C@@H]([C@@H](O)[C@@H](C(N[C@H](C(NCCC4=NC(C5=NC(C(NCCCCN(C(N)=N)CCCCNC(N)=N)=O)=CS5)=CS4)=O)[C@H](O)C)=O)C)C)=O)C6=CNC=N6)O[C@@H](CO)[C@@H](O)[C@@H]2O

Molecular Formula

C60H95N23O21S2

Molecular Weight

1538.67

References & Citations

[1]T P Korobkova, et al. Optimization of the nutrient medium makeup for the biosynthesis of bleomycine antibiotic using a mathematical method of experimental design. Antibiotiki. 1978 Dec;23 (12) :1065-8.|[2]V A Zenkova, et al. Physicochemical and biological properties of bleomycin complex antibiotics. Antibiotiki. 1979 Mar;24 (3) :175-9.|[3]A Yagoda, et al. Bleomycin, an antitumor antibiotic. Clinical experience in 274 patients. Ann Intern Med. 1972 Dec;77 (6) :861-70.