Cavosonstat
Cavosonstat (N91115) is an orally active S-nitrosoglutathione reductase (GSNOR) inhibitor. Cavosonstat is a CFTR stabilizer, and can be used for cystic fibrosis research[1].
Product Specifications
CAS Number
[1371587-51-7]
Product Name Alternative
N91115
UNSPSC
12352005
Target
CFTR; GSNOR
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/cavosonstat.html
Purity
99.36
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
ClC(C=C(C(O)=O)C=C1)=C1C2=NC(C=CC(O)=C3)=C3C=C2
Molecular Formula
C16H10ClNO3
Molecular Weight
299.71
References & Citations
[1]Scott H Donaldson, et al. Pharmacokinetics and safety of cavosonstat (N91115) in healthy and cystic fibrosis adults homozygous for F508DEL-CFTR. J Cyst Fibros. 2017 May;16 (3) :371-379.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 2
Available Sizes
Curated Selection
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