Anti-Ep-CAM / CD326 (Extracellular Domain) (Epithelial Marker)(MOC-31), CF740 conjugate
The epitope of this antibody is located in the first EGF-like repeat domain (EGF1) between amino acids 27-59 of Ep-CAM.EGP40 is a 40-43 kDa transmembrane epithelial glycoprotein, also identified as epithelial specific antigen (ESA), or epithelial cellular adhesion molecule (Ep-CAM). It is expressed on baso-lateral cell surface in most simple epithelia and a vast majority of carcinomas with the exception of adult squamous epithelium, hepatocytes and gastric epithelial cells. This antibody has been used to distinguish adenocarcinoma from pleural mesothelioma and hepatocellular carcinoma. This antibody is also useful in distinguishing serous carcinomas of the ovary from mesothelioma.
Product Specifications
Synonyms
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
TACSTD1
Gene ID
4072
NCBI Gene ID
542050
UniProt
P16422
Cellular Locus
Plasma membrane
Host
Mouse
Species Reactivity
Human
Immunogen
Neuraminidase treated GLS-1 human small cell lung carcinoma cells
Target Antigen
CD326 | Ep-CAM
Clonality
Monoclonal
Isotype
IgG1 κ
Clone
MOC-31
Conjugation
CF740
Disease
Tumor
Source
Animal
Applications
IHC, FFPE (verified) | WB (verified)
Validated Applications
IHC,FFPE,WB
Field of Research
Cancer, Cell adhesion
Positive Control
HT29 cells. Breast tumor.
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% rBSA, 0.05% azide
Molecular Weight
40-43 kDa
Additionnal Information
Shipping Conditions
Room temperature
Storage Conditions
4°C; Protect from light; Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
2 years
Product Datasheet
https://cdn.gentaur.com/products/37/11642565/datasheet/bnc740380-100.pdf
Product MSDS
https://cdn.gentaur.com/products/37/11642565/msds/bnc740380-100.pdf
CAS Number
9007-83-4
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