Isolongifolene

Isolongifolene ((-) -Isolongifolene) is a tricyclic sesquiterpene isolated from Murraya koenigii. Isolongifolene attenuates Rotenone-induced oxidative stress, mitochondrial dysfunction and apoptosis through the regulation of PI3K/AKT/GSK-3β signaling pathways. Isolongifolene has antioxidant, anti-inflammatory, anticancer and neuroprotective properties[1].

Product Specifications

CAS Number

[1135-66-6]

Product Name Alternative

(-) -Isolongifolene

UNSPSC

12352211

Hazard Statement

H225, H301+H311+H331, H370

Target

Apoptosis

Type

Natural Products

Related Pathways

Apoptosis

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Inflammation/Immunology; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/isolongifolene.html

Concentration

10mM

Purity

98.0

Solubility

DMSO : 10 mg/mL (ultrasonic)

Smiles

CC1(C)[C@]23CC[C@](C3)([H])C(C)(C)C2=CCC1

Molecular Formula

C15H24

Molecular Weight

204.35

Precautions

H225, H301+H311+H331, H370

References & Citations

[1]Balakrishnan R, et al. Isolongifolene attenuates rotenone-induced mitochondrial dysfunction, oxidative stress and apoptosis. Front Biosci (Schol Ed) . 2018 Jan 1;10:248-261.