CYP27B1 Recombinant Protein (Mouse)
Product Specifications
Gene Name
Cytochrome P450, family 27, subfamily b, polypeptide 1
Gene Aliases
1alpha (OH) ase;25 (OH) D 1alpha-hydroxylase;25-hydroxyvitamin D (3) 1-alpha-hydroxylase;25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial;25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial precursor (25-OHD-1 alpha-hydroxylase) (25-hydroxyvitamin D3 1-alpha-hydroxylase) (VD3 1A hydroxylase) (P450C1 alpha) (P450VD1-alpha) ;25-hydroxyvitamin D3 1alpha-hydroxylase;25-OHD-1 alpha-hydroxylase; calcidiol 1-monooxygenase; Cp2; Cp2b; Cyp; Cyp1; Cyp27; Cyp27b; Cyp4; Cyp40; cytochrome p450 27B1; cytochrome P450 subfamily XXVIIB polypeptide 1; cytochrome P450, 27b1; cytochrome P450, 40 (25-hydroxyvitamin D3 1 alpha-hydroxylase) ; cytochrome P450C1 alpha; cytochrome P450VD1-alpha; P450c; P450c1; P450VD1alpha; Pd; Pddr; Vd; VD3 1A hydroxylase; Vdd; Vdd1; Vddr; VddrI; Vdr.
Gene ID
13115
Accession Number
NP_034139
Reactivity
Mouse|Mus musculus
Target
Catalyzes the conversion of 25-hydroxyvitamin D3 (25 (OH) D3) to 1-alpha,25-dihydroxyvitamin D3 (1alpha,25 (OH) (2) D3), and of 24,25-dihydroxyvitamin D3 (24,25 (OH) (2) D3) to 1-alpha,24,25-trihydroxyvitamin D3 (1alpha,24,25 (OH) (3) D3) . Is also active with 25-hydroxy-24-oxo-vitamin D3. Plays an important role in normal bone growth, calcium metabolism, and tissue differentiation.
Type
Protein
Source
E.coli
Sequence
MTQAVKLASRVFHRIHLPLQLDASLGSRGSESVLRSLSDIPGPSTLSFLAELFCKGGLSRLHELQVHGAARYGPIWSGSFGTLRTVYVADPTLVEQLLRQESHCPERCSFSSWAEHRRRHQRACGLLTADGEEWQRLRSLLAPLLLRPQAAAGYAGTLDNVVRDLVRRLRRQRGRGSGLPGLVLDVAGEFYKFGLESIGAVLLGSRLGCLEAEVPPDTETFIHAVGSVFVSTLLTMAMPNWLHHLIPGPWARLCRDWDQMFAFAQRHVELREGEAAMRNQGKPEEDMPSGHHLTHFLFREKVSVQSIVGNVTELLLAGVDTVSNTLSWTLYELSRHPDVQTALHSEITAGTRGSCAHPHGTALSQLPLLKAVIKEVLRLYPVVPGNSRVPDRDIRVGNYVIPQDTLVSLCHYATSRDPTQFPDPNSFNPARWLGEGPTPHPFASLPFGFGKRSCIGRRLAELELQMALSQILTHFEVLPEPGALPIKPMTRTVLVPERSINLQFVDR
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Format
Liquid or Lyophilized powder
Buffer
If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
Reconstitution
-20°C or -80°C
Molecular Weight
60.2 kDa
Protein Length
Recombinant
NCBI Gene Symbol
Cyp27b1
Protein Name
25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial
Gene Name URL
Cyp27b1
CAS Number
9000-83-3
Nucleotide Accession Number
NM_010009
Curated Selection
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