Human RNAse l Wild type Recombinant Protein

<strong>Human RNAse l Wild type Recombinant Protein</strong>_x000D_ <strong>Catalog number:</strong> B2012582_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 10 ug_x000D_ <strong>Molecular Weight or Concentration:</strong> 15.79 kDa_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -20°C_x000D_ <strong>Keywords:</strong> RNAse l Wild type, ribonuclease, RNase A family, 1 (pancreatic)_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Zhang A, Dong B, Doucet AJ, Moldovan JB, Moran JV, Silverman RH. RNase L restricts the mobility of engineered retrotransposons in cultured human cells Nucleic Acids Res. 2014 Apr;42(6):3803-20._x000D_ 2: Li Y, Banerjee S, Wang Y, Goldstein SA, Dong B, Gaughan C, Silverman RH, Weiss SR. Activation of RNase L is dependent on OAS3 expression during infection with diverse human viruses Proc Natl Acad Sci U S A. 2016 Feb 23;113(8):2241-6._x000D_ 3: Al-Ahmadi W, Al-Haj L, Al-Mohanna FA, Silverman RH, Khabar KS. RNase L downmodulation of the RNA-binding protein, HuR, and cellular growth Oncogene. 2009 Apr 16;28(15):1782-91._x000D_ 4: Jha BK, Polyakova I, Kessler P, Dong B, Dickerman B, Sen GC, Silverman RH. Inhibition of RNase L and RNA-dependent protein kinase (PKR) by sunitinib impairs antiviral innate immunity J Biol Chem. 2011 Jul 29;286(30):26319-26._x000D_ 5: Siddiqui MA, Malathi K. RNase L induces autophagy via c-Jun N-terminal kinase and double-stranded RNA-dependent protein kinase signaling pathways J Biol Chem. 2012 Dec 21;287(52):43651-64._x000D_ 6: Sorgeloos F, Jha BK, Silverman RH, Michiels T. Evasion of antiviral innate immunity by Theiler's virus L* protein through direct inhibition of RNase L PLoS Pathog. 2013;9(6):e1003474._x000D_ 7: Whelan JN, Li Y, Silverman RH, Weiss SR. Zika Virus Production Is Resistant to RNase L Antiviral Activity J Virol. 2019 Jul 30;93(16):e00313-19._x000D_ 8: Banerjee S, Gusho E, Gaughan C, Dong B, Gu X, Holvey-Bates E, Talukdar M, Li Y, Weiss SR, Sicheri F, Saunthararajah Y, Stark GR, Silverman RH. OAS-RNase L innate immune pathway mediates the cytotoxicity of a DNA-demethylating drug Proc Natl Acad Sci U S A. 2019 Mar 12;116(11):5071-5076._x000D_ 9: Zhao L, Jha BK, Wu A, Elliott R, Ziebuhr J, Gorbalenya AE, Silverman RH, Weiss SR. Antagonism of the interferon-induced OAS-RNase L pathway by murine coronavirus ns2 protein is required for virus replication and liver pathology Cell Host Microbe. 2012 Jun 14;11(6):607-16._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/22875977">10: Chakrabarti A, Ghosh PK, Banerjee S, Gaughan C, Silverman RH. RNase L triggers autophagy in response to viral infections J Virol. 2012 Oct;86(20):11311-21. </a>_x000D_ _x000D_ <strong>Products Related to Human RNAse l Wild type Recombinant Protein can be found at</strong> <a href="https://moleculardepot.com/product-category/Enzymes/"> Enzymes</a>