GSK3β-peptide
Product Specifications
UNSPSC Description
GSK3β-peptide is a substrate mimetic peptide of glycogen synthase kinase 3-β (GSK3-β) that can bind to the active site of GSK3-β and mimic the behavior of a real substrate. GSK3β-peptide can be used to develop substrate mimetic inhibitors of Akt as potential anticancer drugs[1].
Target Antigen
Akt; GSK-3
Type
Peptides
Related Pathways
PI3K/Akt/mTOR;Stem Cell/Wnt
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/gsk3β-peptide.html
Smiles
OC(CC[C@@H](C(O)=O)NC([C@H](C)NC([C@H](CC1=CC=CC=C1)NC([C@H](CO)NC([C@H]([C@H](O)C)NC([C@H]([C@H](O)C)NC([C@H](CCCNC(N)=N)NC([C@H]2N(CCC2)C([C@@H](NC(CN)=O)CCCNC(N)=N)=O)=O)=O)=O)=O)=O)=O)=O)=O
Molecular Weight
1121.20
References & Citations
[1]Kayser, et al. "Modifications of the GSK3β substrate sequence to produce substrate-mimetic inhibitors of Akt as potential anti-cancer therapeutics." Bioorganic & medicinal chemistry letters 17.7 (2007): 2068-2073.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-P10605/GSK3β-peptide-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-P10605/
Clinical Information
No Development Reported
CAS Number
496856-73-6
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