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PTPRZ1 Antibody - N-terminal region

Product Specifications

Gene Name

Protein tyrosine phosphatase, receptor-type, Z polypeptide 1

Gene Aliases

PTPZ, HPTPZ, PTP18, PTPRZ, RPTPB, HPTPzeta, PTP-ZETA, RPTPbeta, phosphacan, R-PTP-zeta-2

Gene ID

5803

Reactivity

Human, Mouse, Rat

Immunogen

Synthesized peptide derived between 100-180 aa from N-terminal region of human PTPzeta.

Target

Protein tyrosine phosphatase that negatively regulates oligodendrocyte precursor proliferation in the embryonic spinal cord. Required for normal differentiation of the precursor cells into mature, fully myelinating oligodendrocytes. May play a role in protecting oligondendrocytes against apoptosis. May play a role in the establishment of contextual memory, probably via the dephosphorylation of proteins that are part of important signaling cascades .

Clonality

Polyclonal

Type

Polyclonal Antibody

Applications

WB

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

1 mg/ml

Format

Liquid.//PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide

Reconstitution

Store at -20C, and avoid repeat freeze-thaw cycles.

Molecular Weight

250 kDa

Fragment

IgG

Specificity

PTPzeta Polyclonal Antibody detects endogenous levels of PTPzeta protein.

NCBI Gene Symbol

PTPRZ1

Host or Source

Rabbit

Gene Name URL

PTPRZ1

CAS Number

9007-83-4

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