Human CD3 Antibody : Biotin
Product Specifications
Gene Name
T-cell surface glycoprotein CD3 epsilon chain
Gene Aliases
T3E, TCRE, IMD18
Gene ID
916
Accession Number
NP_000724.1
Reactivity
Human
Immunogen
Human peripheral blood lymphocytes from a patient with Sezary's syndrome and infant thymocytes
Target
The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women.
Clonality
Monoclonal
Clone
UCHT1
Conjugation
Biotin
Type
Monoclonal Antibody
Applications
FC, IHC-F, IHC-P, ICC, IP, WB
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
Lot specific
Dilution
6 cells
10 uL/106 cells
10 uL/106 cells
10 uL/106 cells
10 uL/106 cells
10 uL/106 cells
10 uL/106 cells
10 uL/106 cells
10 uL/106 cells
10 uL/106 cells666666666
Reconstitution
Store at 2-8C
Notes
Formerly GWB-459E3E
Fragment
IgG1
Specificity
CD3
NCBI Gene Symbol
CD3E
Host or Source
Mouse
Protein Name
T-cell surface glycoprotein CD3 epsilon chain
Gene Name URL
CD3E
CAS Number
9007-83-4
Nucleotide Accession Number
NM_000733.3
Curated Selection
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