TGM3 Antibody
Product Specifications
Gene Name
Transglutaminase 3, E polypeptide
Gene Aliases
AI893889; E polypeptide; protein-glutamine gamma-glutamyltransferase E; protein-glutamine-gamma-glutamyltransferase; TG E; TG (E) ; TGase E; TGase-3; TGE; transglutaminase E; transglutaminase-3; we.
Gene ID
21818
Accession Number
NP_033400.2
Reactivity
Mouse|Rat
Immunogen
Range: Ala468 - Glu693
Target
Catalyzes the calcium-dependent formation of isopeptide cross-links between glutamine and lysine residues in various proteins, as well as the conjugation of polyamines to proteins. Involved in the formation of the cornified envelope (CE), a specialized component consisting of covalent cross-links of proteins beneath the plasma membrane of terminally differentiated keratinocytes. Catalyzes small proline-rich proteins (SPRR1 and SPRR2) and LOR cross-linking to form small interchain oligomers, which are further cross-linked by TGM1 onto the growing CE scaffold (By similarity) . In hair follicles, involved in cross-linking structural proteins to hardening the inner root sheath.
Clonality
Polyclonal
Type
Polyclonal Antibody
Applications
Immunocytochemistry|Immunohistochemistry|Immunoprecipitation|Western blot
Purification
Affinity Purified; Protein A Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
0.5 mg/ml
Format
Liquid. PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Reconstitution
2°C to 8°C|-20°C
Molecular Weight
77 kDa
Fragment
IgG
Specificity
The antibody is a rabbit polyclonal antibody raised against TGM3. It has been selected for its ability to recognize TGM3 in immunohistochemical staining and western blotting.
NCBI Gene Symbol
Tgm3
Host or Source
Rabbit
Protein Name
Protein-glutamine gamma-glutamyltransferase E
Gene Name URL
Tgm3
CAS Number
9007-83-4
Nucleotide Accession Number
NM_009374
Curated Selection
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