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ICOSL Antibody

Product Specifications

Gene Name

Icos ligand

Gene Aliases

AU044799; B7 homolog 2; B7h; B7-H2; B7-like protein Gl50; B7-related protein 1; B7RP; B7RP-1; BG071784; GI50; GL5; GL50; GL50-; GL50-B; IC; ICOS ligand; ICOS-L; Icoslg; L; LICOS; Ly115l; mKIAA0653.

Gene ID

50723

Accession Number

NP_056605.1

Reactivity

Mouse

Immunogen

Range: Val58 - Leu249

Target

Ligand for the T-cell-specific cell surface receptor ICOS. Acts as a costimulatory signal for T-cell proliferation and cytokine secretion; induces also B-cell proliferation and differentiation into plasma cells. Could play an important role in mediating local tissue responses to inflammatory conditions, as well as in modulating the secondary immune response by co-stimulating memory T-cell function. During pregnancy, may function to skew the cytokine of maternal T-cells toward immunoprotective Th2 phenotype.

Clonality

Polyclonal

Type

Polyclonal Antibody

Applications

Immunocytochemistry|Immunohistochemistry|Immunoprecipitation|Western blot

Purification

Affinity Purified; Protein A Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

1 mg/ml

Format

Liquid. PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.

Reconstitution

2°C to 8°C|-20°C

Molecular Weight

36 kDa

Fragment

IgG

Specificity

The antibody is a rabbit polyclonal antibody raised against ICOSLG. It has been selected for its ability to recognize ICOSLG in immunohistochemical staining and western blotting.

NCBI Gene Symbol

Icosl

Host or Source

Rabbit

Protein Name

ICOS ligand

Gene Name URL

Icosl

CAS Number

9007-83-4

Nucleotide Accession Number

NM_015790

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