DR1 Antibody
Product Specifications
Gene Name
Down-regulator of transcription 1
Gene Aliases
Down-regulator of transcription 1; NC2; NC2B; NC2-BETA; NCB2; negative cofactor 2; negative cofactor 2-beta; protein Dr1; TATA-binding protein-associated phosphoprotein.
Gene ID
1810
Accession Number
NP_001929.1
Reactivity
Human|Mouse
Immunogen
Range: Ala2 - Glu170
Target
The association of the DR1/DRAP1 heterodimer with TBP results in a functional repression of both activated and basal transcription of class II genes. This interaction precludes the formation of a transcription-competent complex by inhibiting the association of TFIIA and/or TFIIB with TBP. Can bind to DNA on its own. Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4.
Clonality
Polyclonal
Type
Polyclonal Antibody
Applications
Immunocytochemistry|Immunohistochemistry|Immunoprecipitation|Western blot
Purification
Affinity Purified; Protein A Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
0.5 mg/ml
Format
Liquid. PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Reconstitution
2°C to 8°C|-20°C
Molecular Weight
19 kDa
Fragment
IgG
Specificity
The antibody is a rabbit polyclonal antibody raised against DR1. It has been selected for its ability to recognize DR1 in immunohistochemical staining and western blotting.
NCBI Gene Symbol
DR1
Host or Source
Rabbit
Protein Name
Protein Dr1
Gene Name URL
DR1
CAS Number
9007-83-4
Nucleotide Accession Number
NM_001938
Curated Selection
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