Dofetilide
Dofetilide (UK 68789), as a class III antiarrhythmic agent, is an orally active, potent and specific IKr blocker. Dofetilide can be used for the research of cardiovascular disease[1][2].
Product Specifications
CAS Number
[115256-11-6]
Product Name Alternative
UK 68789
UNSPSC
12352005
Hazard Statement
H360
Target
Potassium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
COVID-19-immunoregulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/Dofetilide.html
Purity
98.84
Solubility
DMSO : ≥ 100 mg/mL
Smiles
CS(=O)(NC1=CC=C(CCN(C)CCOC2=CC=C(NS(=O)(C)=O)C=C2)C=C1)=O
Molecular Formula
C19H27N3O5S2
Molecular Weight
441.56
Precautions
H360
References & Citations
[1]Mounsey JP, et al. Cardiovascular drugs. Dofetilide. Circulation. 2000;102 (21) :2665-2670.|[2]Gwilt M, et al. Dofetilide, a new class III antiarrhythmic agent, reduces pacing induced heterogeneity of repolarisation in vivo. Cardiovasc Res. 1992;26 (11) :1102-1108.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched
Available Sizes
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