PARD3 Antibody

Product Specifications

CAS Number

9007-83-4

Gene Name

Par-3 family cell polarity regulator

Gene Aliases

ASIP; atypical PKC isotype-specific interacting protein; Atypical PKC isotype-specific-interacting protein; Baz; bazooka; CTCL tumor antigen se2-5; PAR3; par-3 family cell polarity regulator alpha; par-3 partitioning defective 3 homolog; PAR3alpha; PAR3-alpha; PARD-3; PARD3A; partitioning defective 3 homolog; PPP1R118; protein phosphatase 1, regulatory subunit 118; SE2-5L16; SE2-5LT1; SE2-5T2.

Gene ID

56288

Accession Number

NP_001171714

Reactivity

Human

Immunogen

Recombinant Human Partitioning defective 3 homolog protein (1068-1356AA)

Target

Adapter protein involved in asymmetrical cell division and cell polarization processes (PubMed:27925688, PubMed:10954424) . Seems to play a central role in the formation of epithelial tight junctions (PubMed:27925688) . Targets the phosphatase PTEN to cell junctions (By similarity) . Involved in Schwann cell peripheral myelination (By similarity) . Association with PARD6B may prevent the interaction of PARD3 with F11R/JAM1, thereby preventing tight junction assembly (By similarity) . The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins (PubMed:10934474) . Required for establishment of neuronal polarity and normal axon formation in cultured hippocampal neurons (PubMed:19812038, PubMed:27925688) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Polyclonal Antibody

Applications

Enzyme-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry|Western blot

Purification

Protein G Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol