CDC2
Product Specifications
Gene Name
Cyclin-dependent kinase 1
Gene Aliases
CDC2, CDC28A, P34CDC2
Gene ID
983
Swiss Prot
P06493
Accession Number
NP_001777
Reactivity
Human
Immunogen
The immunogen is a synthetic peptide directed towards the C terminal region of human CDC2
Target
The protein encoded by CDC2 is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of this protein is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control. The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of this protein is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control.
Partner Proteins
ABL1; SIRT1; CDC37; HUWE1; BTRC; UBC; HSP90AA1; HSPA4; HIST1H1A; GADD45A; CKS1B; USP16; Samhd1; UIMC1; SUMO2; CCNA2; STAU1; RNF2; CKS2; ZRANB2; CDKN1B; CDKN1A; CDK1; CCNB1; FBXO6; CCNB2; PKMYT1; SQSTM1; EGFR; PTMA; DCTN6; RGCC; BAG3; CDC25B; BCL2; TP53BP1
Clonality
Polyclonal
Type
Polyclonal Antibody
Sequence
SLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFNDLDNQIKKM
Applications
IHC, WB
Purification
Affinity Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
0.5 mg/ml
Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Molecular Weight
34kDa
Protein Length
297
NCBI Gene Symbol
CDK1
Host or Source
Rabbit
Protein Name
Cyclin-dependent kinase 1
Gene Name URL
CDK1
Nucleotide Accession Number
NM_001786
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