NCOA2 Antibody - N-terminal region
Product Specifications
Gene Name
Nuclear receptor coactivator 2
Gene Aliases
SRC2, TIF2, GRIP1, KAT13C, NCoA-2, bHLHe75
Gene ID
10499
Swiss Prot
Q15596
Accession Number
NP_001308632.1
Reactivity
Human
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human NCOA2
Target
The protein encoded by this gene functions as a transcriptional coactivator for nuclear hormone receptors, including steroid, thyroid, retinoid, and vitamin D receptors. The encoded protein acts as an intermediary factor for the ligand-dependent activity of these nuclear receptors, which regulate their target genes upon binding of cognate response elements. This gene has been found to be involved in translocations that result in fusions with other genes in various cancers, including the lysine acetyltransferase 6A (KAT6A) gene in acute myeloid leukemia, the ETS variant 6 (ETV6) gene in acute lymphoblastic leukemia, and the hes related family bHLH transcription factor with YRPW motif 1 (HEY1) gene in mesenchymal chondrosarcoma. Alternative splicing results in multiple transcript variants.
Clonality
Polyclonal
Type
Polyclonal Antibody
Sequence
PSPKRNTEKRNREQENKYIEELAELIFANFNDIDNFNFKPDKCAILKETV
Applications
WB
Purification
Affinity purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
0.5 mg/ml
Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Molecular Weight
161 kDa
Protein Length
1464
NCBI Gene Symbol
NCOA2
Host or Source
Rabbit
Protein Name
Nuclear receptor coactivator 2
Gene Name URL
NCOA2
CAS Number
9007-83-4
Nucleotide Accession Number
NM_001321703.1
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
GTR15080428 1 Vial
Lentiviral human TINAGL1 shRNA (UAS) - Lentiviral human TINAGL1 shRNA (UAS, iRFP) plasmid
Ask
View Details 