PDLIM7 Antibody - middle region
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Product Specifications
Gene Name
PDZ and LIM domain 7
Gene Aliases
LMP1, LMP3
Gene ID
9260
Swiss Prot
Q9NR12
Reactivity
Human
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of Human PDLI7
Target
The protein encoded by this gene is representative of a family of proteins composed of conserved PDZ and LIM domains. LIM domains are proposed to function in protein-protein recognition in a variety of contexts including gene transcription and development and in cytoskeletal interaction. The LIM domains of this protein bind to protein kinases, whereas the PDZ domain binds to actin filaments. The gene product is involved in the assembly of an actin filament-associated complex essential for transmission of ret/ptc2 mitogenic signaling. The biological function is likely to be that of an adapter, with the PDZ domain localizing the LIM-binding proteins to actin filaments of both skeletal muscle and nonmuscle tissues. Alternative splicing of this gene results in multiple transcript variants.
Partner Proteins
WWP2; IQGAP1; TSG101; PHF1; DGCR6; BAG3; RET; CBLC; COPS5; PARP1; YAP1; HNRNPD; PRKD2; ZMYND11; TRADD; UBC; SH3BP2; MYC; Hoxa1; NDUFA7; PCBP1; UBQLN4; TRAF3; TRAF2; TAB2; TRAF6; NR2C2; SMURF1; TP53; MDM2; Cdk1; PSMF1; SH2B2; C20orf195; AP5B1; ENKD1; TPM2
Clonality
Polyclonal
Type
Polyclonal Antibody
Sequence
SSTPQEPWPGPTAPSPTSRPPWAVDPAFAERYAPDKTSTVLTRHSQPATP
Applications
WB
Purification
Affinity purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
0.5 mg/ml
Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Molecular Weight
50kDa
Protein Length
457
NCBI Gene Symbol
PDLIM7
Host or Source
Rabbit
Protein Name
PDZ and LIM domain protein 7
Gene Name URL
PDLIM7
CAS Number
9007-83-4
Curated Selection
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