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HIST1H4A Antibody - N-terminal region (ARP70540_P050)

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Product Specifications

Gene Aliases

H4C2, H4C3, H4C4, H4C5, H4C6, H4C8, H4C9, H4FA, H4-16, H4C11, H4C12, H4C13, H4C14, H4C15, HIST1H4A

Gene ID

8359

Swiss Prot

P62805

Accession Number

NP_778224

Reactivity

Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N-terminal region of Human HIST1H4A

Target

HIST1H4A is a core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Partner Proteins

UBC; DTX3L; RBBP4; H3F3A; CENPA; HIST1H3A; HDAC2; ASB9; ASB16; L3MBTL2; rev; ARFIP1; JMJD6; XPO7; FAF1; HSPH1; SEC23A; PRMT3; RBX1; HIRIP3; CUL1; ZYX; SF1; TTC1; TROVE2; SHMT1; RPL24; PPM1G; OSBP; GFPT1; GARS; CARS; FBXO6; PAN2; PRMT8; RL1; HCVgp1; ITGA4

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

LGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLK

Applications

WB

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Goat: 100%; Guinea Pig: 100%; Mouse: 100%; Rat: 100%; Zebrafish: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

11kDa

Protein Length

103

NCBI Gene Symbol

HIST1H4A

Host or Source

Rabbit

Protein Name

Histone H4

Gene Name URL

HIST1H4A

CAS Number

9007-83-4

Nucleotide Accession Number

NM_175054

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