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CD4 antibody - C-terminal region (ARP59105_P050)

Product Specifications

Gene Name

CD4 molecule

Gene Aliases

IMD79, OKT4D, CD4mut

Gene ID

920

Swiss Prot

P01730

Accession Number

NP_000607

Reactivity

Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Rabbit, Sheep

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human CD4

Target

This gene encodes a membrane glycoprotein of T lymphocytes that interacts with major histocompatibility complex class II antigenes and is also a receptor for the human immunodeficiency virus. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, and granulocytes. It is also expressed in specific regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene.

Partner Proteins

Env; RANBP9; vpu; ADRB2; UBC; CXCR4; UBL7; ABCB1; INPPL1; VCP; HGS; LCK; NR3C1; STUB1; TUBB; MYL12A; DHRS2; LRPPRC; FARSB; EIF3I; EIF3D; EIF3C; EIF3B; VIM; VDAC3; VDAC2; VDAC1; SSRP1; RPS19; RPS12; RPS10; RPS9; RPLP1; RPLP0; RPL22; RPL18; RPL7; PHB; NPM1

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

VLGGVAGLLLFIGLGIFFCVRCRHRRRQAERMSQIKRLLSEKKTCQCPHR

Applications

WB

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Goat: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 100%; Sheep: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

48kDa

Protein Length

458

NCBI Gene Symbol

CD4

Host or Source

Rabbit

Protein Name

T-cell surface glycoprotein CD4

Gene Name URL

CD4

CAS Number

9007-83-4

Nucleotide Accession Number

NM_000616

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