CBR-470-2

CBR-470-2, a glycine-substituted analog, can activate NRF2 signaling. CBR-470-2 can be used for the research of modulation glycolysis[1].

Product Specifications

CAS Number

[2416095-00-4]

UNSPSC

12352005

Target

Keap1-Nrf2

Type

Reference compound

Related Pathways

NF-κB

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/cbr-470-2.html

Purity

99.45

Solubility

DMSO : 200 mg/mL (ultrasonic)

Smiles

OC(CN[C@@H](C1)[C@@H](S(C2=CC=C(Cl)C(Cl)=C2)(=O)=O)CS1(=O)=O)=O

Molecular Formula

C12H13Cl2NO6S2

Molecular Weight

402.27

References & Citations

[1]Bollong MJ, et, al. A metabolite-derived protein modification integrates glycolysis with KEAP1-NRF2 signalling. Nature. 2018 Oct;562 (7728) :600-604.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, stored under nitrogen)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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