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Anti-ENG

Product Specifications

CAS Number

9007-83-4

Gene Name

Endoglin

Gene Aliases

END, HHT1, ORW1

Gene ID

2022

Swiss Prot

P17813

Accession Number

NP_000109

Reactivity

Human, Mouse, Rat, Guinea Pig

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human ENG

Target

Endoglin is a homodimeric transmembrane glycoprotein highly expressed by endothelial cells. It is a component of the transforming growth factor beta receptor complex since it binds TGFB1 and TGFB3 with high affinity. Mutations in the endoglin gene produce hereditary hemorrhagic telangiectasia.

Partner Proteins

ENG; TGFBR2; TGFBR1; TGFB3; TGFB1; ACVRL1; TUFM; TCTEX1D4; TGFBR3; TGFB2; INHBA; BMP7; BMP2; ACVR2A; ACVR1; ACVR2B

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

ILEVHVLFLEFPTGPSQLELTLQASKQNGTWPREVLLVLSVNSSVFLHLQ

Applications

IHC, WB

Purification

Protein A purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

1.0 mg/ml

Homology

Guinea Pig: 91%; Human: 100%; Mouse: 91%; Rat: 91%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

68kDa

Protein Length

625

NCBI Gene Symbol

ENG

Host or Source

Rabbit

Protein Name

Endoglin

Gene Name URL

ENG

Nucleotide Accession Number

NM_000118

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