14,15-EET-SI
Product Specifications
UNSPSC Description
14,15-EET-SI is a sulfonimide (SI) analog metabolized from 14,15-EET, which is also an effective mitogen. 14,15-EET-SI can stimulate the incorporation of [3H] thymidine, activate pp60c-src and initiate the tyrosine kinase cascade, mediating their mitotic effects. Additionally, 14,15-EET-SI can increase cell proliferation as well as the expression of c-fos and egr-1 mRNA[1].
Target Antigen
Others
Type
Reference compound
Related Pathways
Others
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/14-15-eet-si.html
Solubility
10 mM in DMSO
Smiles
CS(NC(CCC/C=C\C/C=C\C/C=C\CC1C(O1)CCCCC)=O)(=O)=O
Molecular Weight
397.57
References & Citations
[1]Chen JK, et al. Epoxyeicosatrienoic acids and their sulfonimide derivatives stimulate tyrosine phosphorylation and induce mitogenesis in renal epithelial cells. J Biol Chem. 1998 Oct 30;273(44):29254-61.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-131721/14-15-EET-SI-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-131721/
Clinical Information
No Development Reported
CAS Number
218461-97-3
Available Sizes
Curated Selection
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