HDAC/HSP90-IN-4
Product Specifications
Target
Others|||HSP|||HDAC
Related Pathways
Cytoskeletal Signaling|||Metabolism|||DNA Damage/DNA Repair|||Others|||Chromatin/Epigenetic
Bioactivity
HDAC/HSP90-IN-4 significantly inhibited HDAC and HSP90 activity, with compound 20 (HDACIC50= 194 nM; HSP90?IC50= 153 nM) and compound 26 ((HDACIC50= 360 nM; HSP90?IC50= 77 nM) having the strongest HDAC and HSP90? inhibition. effect. Both compounds induced HSP90 expression and down-regulated HSP90 client proteins, which play an important role in the regulation of cancer cell survival and invasion.
Molecular Formula
C20H23N3O6
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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