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A?1–42 aggregation inhibitor 1

Product Specifications

CAS Number

2439107-75-0

Target

Beta Amyloid|||Cholinesterase (ChE) |||Others

Related Pathways

Others|||Neuroscience

Bioactivity

A?1-42 aggregation inhibitor 1 effectively inhibits acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE) with IC50 values of 2.64 ?M and 1.29 ?M, respectively. At 25 ?M, it also reduces self-mediated A?1-42 aggregation by 51.29%, showcasing its potential for Alzheimer's disease research [1].

Smiles

C(C)N1C=2C(C=3C1=CC=CC3)=CC(/C=C/C4=CC=C(NC(NCCN5CCCC5)=S)C=C4)=CC2

Molecular Formula

C29H32N4S

Molecular Weight

468.66

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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