WF-47-JS03
Product Specifications
Target
Others|||c-RET
Related Pathways
Tyrosine Kinase/Adaptors|||Apoptosis|||Others
Bioactivity
WF-47-JS03 is a selective and potent inhibitor of RET kinase that crosses the blood-brain barrier and is more than 500-fold more selective for the kinase insertion domain receptor (KDR) .WF-47-JS03 acts on Ba/F3 cells transfected with KIF5B-RET (IC50: 1.7 nM) and LC-2/ad lung cancer cells transfected with CCDC6-RET (IC50: 5.3 nM) . cells (IC50: 5.3 nM) .
Molecular Formula
C30H38N6O2
Molecular Weight
514.66
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Product Datasheet
https://www.targetmol.com/attachment/DataSheet/527BF8B7-F948-46E0-ACBE-B635478831DA/T63573
Available Sizes
Curated Selection
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