MA242 free base
Product Specifications
CAS Number
1049704-17-7
Target
MDM-2/p53|||Apoptosis|||Others
Related Pathways
Apoptosis|||Others
Bioactivity
MA242 free base is a specific dual inhibitor of MDM2 and NFAT1 that induces apoptosis in pancreatic cancer cell lines. It binds directly to MDM2 and NFAT1 with high affinity, induces their protein degradation, and inhibits NFAT1-mediated MDM2 transcription.
Smiles
S(=O)(=O)(N1C2=C3C(=C1)CCN=C3C=C(NCC4=CC=C(Cl)C=C4)C2=O)C5=CC=C(C)C=C5
Molecular Formula
C24H20ClN3O3S
Molecular Weight
465.95
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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