UNC9994 hydrochloride
Product Specifications
CAS Number
2108826-33-9
Target
5-HT Receptor|||Dopamine Receptor|||Arrestin|||Others
Related Pathways
Neuroscience|||GPCR/G Protein|||Others
Bioactivity
UNC9994 hydrochloride is a functionally selective, ?-arrestin-biased dopamine D2 receptor (D2R) agonist (Ki: 79 nM) that selectively activates ?-arrestin recruitment and signal transduction. UNC9994 hydrochloride is a Gi-regulated antagonist of cAMP production and a partial agonist of the D2R/?-arrestin-2 interaction, exhibiting psychostimulatory effects.
Smiles
Cl.Clc1cccc(C2CCN(CCCOc3ccc4scnc4c3)CC2)c1Cl
Molecular Formula
C21H23Cl3N2OS
Molecular Weight
457.84
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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