Anticancer agent 63
Product Specifications
CAS Number
2529657-32-5
Target
Caspase|||Apoptosis|||Bcl-2 Family|||Others
Related Pathways
Proteases/Proteasome|||Others|||Apoptosis
Bioactivity
Anticancer agent 63 (compound 3h) exhibits significant cytotoxic activity against multiple cancer cell lines, including SW480, HeLa, A549, and MCF-7, with IC50 values of 4.9, 11.5, 9.4, and 3.4 ?M, respectively, after 24 hours of treatment. It induces apoptosis in MCF-7 cells by down-regulating Bcl-2 expression and up-regulating IL-2 and Caspase-3 expression, and also demonstrates antioxidative properties [1].
Smiles
C(C(NCCC[Se]C(F)(F)F)=O)(C)C1=CC=C(CC(C)C)C=C1
Molecular Formula
C17H24F3NOSe
Molecular Weight
394.33
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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