USP15-IN-1
Product Specifications
CAS Number
2260826-16-0
Target
DUB
Related Pathways
DNA Damage/DNA Repair|||Ubiquitination|||Cell Cycle/Checkpoint
Purity
0.9981
Bioactivity
USP15-IN-1 is a potent USP15 inhibitor (IC50 is 3.76 ?M) with high antiproliferative activity against non-small cell lung cancer and leukemia cells. As an interacting protein of cGAS, USP15 promotes cGAS to recognize DNA and activate downstream signaling pathways.
Smiles
OCCNC(=O)c1ccc2[nH]c3CN(CCc3c2c1)C(=O)Cc1ccccc1
Molecular Formula
C22H23N3O3
Molecular Weight
377.44
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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