Anti-Influenza agent 3

Anti-Influenza agent 3 (compound 11h) is a potent anti-influenza agent with low cytotoxicity for MDCK epithelial cells, inhibiting the M2 WT and S31N ion channel conductivity. It has an EC50 value of 3.29 ?M for A/HK/68 (H3N2, M2-WT) and 2.45 ?M for A/WSN/33 (H1N1, M2-S31N) strain [1].