Ebopiprant
Ebopiprant (OBE022) is an oral and selective prostaglandin F2α (PGF2α) receptor antagonist, with Kis of 1 nM, 26 nM for human and rat FP receptors, respectively.
Product Specifications
CAS Number
[2005486-31-5]
Product Name Alternative
OBE022
UNSPSC
12352005
Target
Prostaglandin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Endocrinology
Assay Protocol
https://www.medchemexpress.com/OBE022.html
Concentration
10mM
Purity
98.65
Solubility
DMSO : 250 mg/mL (ultrasonic)
Smiles
O=C(N[C@H](C1=CC=C(F)C=C1)CCOC([C@H](C(C)C)N)=O)[C@H](SCC2)N2S(C(C=C3)=CC=C3C4=CC=CC=C4)(=O)=O
Molecular Formula
C30H34FN3O5S2
Molecular Weight
599.74
References & Citations
[1]Oliver Pohl, et al. OBE022, an oral and selective prostaglandin F2α receptor antagonist as an effective and safe modality for the treatment of preterm labor. J Pharmacol Exp Ther. 2018 Aug;366 (2) :349-364.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 2
Isoform
FP
Available Sizes
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